The following effects are indicative of excessive dosage, and usually disappear on reduction of dosage or withdrawal of treatment for a few days. Anginal pain, cardiac arrhythmias, palpitation, and cramps in skeletal muscle; also tachycardia, diarrhea, vomiting, tremors, restlessness, excitability, insomnia, headache, flushing, sweating, excessive loss of weight and muscular weakness. Rarely hypersensitivity reactions such as skin rash and pruritis have been reported. Rare cases of pseudotumour cerebri (benign intracranial hypertension) have been reported, especially in children.